Molecular Analysis of the Systemic Dermatoses of Morgellons Disease
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Molecular Analysis of the Systemic Dermatoses of Morgellons Disease Samantha Rice, Randy Wymore Graduate Student ResearchResearch OpportunitiesPharmacology and Physiology Research output: Contribution to conference › Poster › peer-review Overview Fingerprint Abstract Morgellons disease (MD) is a multisystem infectious disease historically viewed as controversial and poorly understood by the medical community.1,2,3,4,6,8 These contentions involve difficulties in diagnosis, as symptoms of MD have similarities consistent with a psychiatric disorder involving the false beliefs of infestation by parasites, also known as delusional parasitosis or delusional infestation.1,2,3,6 Currently, the factors determining the etiology and transmission of MD are still unknown and the dispute surrounding Morgellons is substantial. The aim of this study is to investigate if an infectious etiology of systemic dermatoses is present. Epithelial tissue samples are collected and deidentified remaining anonymous to researchers. Molecular biology tools are implemented for the detection of unusual microbial organisms, specifically, Bartonella henselae, Borrelia burgdorferi, Helicobacter pylori, and Treponema denticola. Previous research endeavors suggest MD is a disorder associated with a tick-borne illness, caused by the bacterium Borrelia burgdorferi, a pathogenic spirochete and the causative agent of Lyme disease (LD).8,15 MD studies are currently focused on spirochetes as the causative agent to understand if a coinfection exists and/or if multifactorial etiology is a cohort. We hypothesize the presence of multiple pathogenic organisms found in dermatological specimens suggesting infectious pathogens in MD etiology. Recognition of the potential coexistence of multiple pathogens in MD etiology may stimulate the development of novel approaches to diagnosis and treatment. Therefore, allowing multiple diagnostic approaches to be applied simultaneously to detect for the major pathogens in MD. Original languageAmerican EnglishPages94StatePublished - 17 Feb 2023EventOklahoma State University Center for Health Sciences Research Week 2023 - Oklahoma State University Center for Health Sciences, 1111 W. 17th street, Tulsa, United StatesDuration: 13 Feb 2023 → 17 Feb 2023https://medicine.okstate.edu/events/index.html?trumbaEmbed=view%3Devent%26eventid%3D160681489ConferenceConferenceOklahoma State University Center for Health Sciences Research Week 2023Country/TerritoryUnited StatesCityTulsaPeriod13/02/23 → 17/02/23Internet addresshttps://medicine.okstate.edu/events/index.html?trumbaEmbed=view%3Devent%26eventid%3D160681489 KeywordsMorgellons diseaseLyme diseasefibersetiologyBorrelia burgdorferi Access to Document https://youtu.be/mTo8Sh2QRgEhttps://hdl.handle.net/20.500.14446/339903 Fingerprint Dive into the research topics of 'Molecular Analysis of the Systemic Dermatoses of Morgellons Disease'. Together they form a unique fingerprint. Molecular Analysis Keyphrases 100% Morgellons Disease Keyphrases 100% Dermatosis Keyphrases 100% Causative Agents Keyphrases 22% Borrelia Burgdorferi Keyphrases 22% Disease Etiology Keyphrases 22% Spirochetes Keyphrases 22% Infectious Diseases Keyphrases 11% View full fingerprint Cite this APA Author BIBTEX Harvard Standard RIS Vancouver Rice, S., & Wymore, R. (2023). Molecular Analysis of the Systemic Dermatoses of Morgellons Disease. 94. Poster session presented at Oklahoma State University Center for Health Sciences Research Week 2023, Tulsa, Oklahoma, United States. https://youtu.be/mTo8Sh2QRgE Rice, Samantha ; Wymore, Randy. / Molecular Analysis of the Systemic Dermatoses of Morgellons Disease. Poster session presented at Oklahoma State University Center for Health Sciences Research Week 2023, Tulsa, Oklahoma, United States. @conference{657213978ec844718fb697d98a007cb5, title = "Molecular Analysis of the Systemic Dermatoses of Morgellons Disease", abstract = "Morgellons disease (MD) is a multisystem infectious disease historically viewed as controversial and poorly understood by the medical community.1,2,3,4,6,8 These contentions involve difficulties in diagnosis, as symptoms of MD have similarities consistent with a psychiatric disorder involving the false beliefs of infestation by parasites, also known as delusional parasitosis or delusional infestation.1,2,3,6 Currently, the factors determining the etiology and transmission of MD are still unknown and the dispute surrounding Morgellons is substantial. The aim of this study is to investigate if an infectious etiology of systemic dermatoses is present. Epithelial tissue samples are collected and deidentified remaining anonymous to researchers. Molecular biology tools are implemented for the detection of unusual microbial organisms, specifically, Bartonella henselae, Borrelia burgdorferi, Helicobacter pylori, and Treponema denticola. Previous research endeavors suggest MD is a disorder associated with a tick-borne illness, caused by the bacterium Borrelia b...